Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 5/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.57 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633688 | 0.91 | KDR (0.52) | PDGFRAKDRMETMAOB | |
| SCHEMBL12003929 | 0.84 | CTSV (0.50) | PDGFRAKDRKDM4EMEN1POLB | |
| SCHEMBL15537365 | 0.84 | KDR (0.63) | PDGFRAKDRMETFGFR2PDGFRB | |
| SCHEMBL19633698 | 0.83 | TUBB1 (0.57) | METTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL19633697 | 0.81 | GAK (0.53) | PDGFRAKDRMETTUBB1TUBB4A | |
| SCHEMBL19633823 | 0.81 | PDGFRA (0.52) | PDGFRAKDRMETMAOBPDGFRB | |
| SCHEMBL19633628 | 0.80 | PDGFRA (0.53) | PDGFRAKDRMETHTTMEN1 | |
| SCHEMBL19633777 | 0.79 | GAK (0.57) | PDGFRAKDRGAKRIPK2COQ8A | |
| SCHEMBL558651 | 0.79 | PDGFRA (0.80) | PDGFRAKDRMETFGFR2PDGFRB | |
| SCHEMBL19633577 | 0.79 | KDR (0.50) | PDGFRAKDRMETMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |