Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | GALR2 | O43603 | 1/20 | 0.30 |
| ▸ | GALR1 | P47211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634133 | 0.77 | HTR2A (0.38) | MAPTMEN1KMT2AKDM4ESCN8A | |
| SCHEMBL19634248 | 0.74 | KDM4E (0.36) | MAPTMEN1KMT2AKDM4ESCN8A | |
| SCHEMBL19634139 | 0.73 | MAPT (0.39) | MAPTP2RX3MEN1KMT2AEPHX2 | |
| SCHEMBL22646292 | 0.72 | P2RX3 (0.40) | MAPTP2RX3KDM4ESCN8ASCN9A | |
| SCHEMBL19633963 | 0.71 | SCN8A (0.42) | MAPTP2RX3SCN8ASCN9A | |
| SCHEMBL19614151 | 0.71 | SCN8A (0.42) | MAPTP2RX3SCN8ASCN9A | |
| SCHEMBL21117671 | 0.71 | SCN1A (0.41) | MAPTP2RX3EPHX2SCN8ASCN9A | |
| SCHEMBL19634333 | 0.70 | SCN1A (0.33) | KDM4ESCN8A | |
| SCHEMBL19634257 | 0.70 | SCN8A (0.39) | SCN8A | |
| SCHEMBL20256322 | 0.68 | SCN8A (0.51) | SCN8ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |