Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 4/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634257 | 0.85 | SCN8A (0.39) | SCN1ASCN8A | |
| SCHEMBL19634248 | 0.81 | KDM4E (0.36) | SCN1ASCN8AKDM4ENR1I2SCN1B | |
| SCHEMBL19634133 | 0.79 | HTR2A (0.38) | SCN1ASCN8AKDM4ENR1I2SCN1B | |
| SCHEMBL19613495 | 0.74 | SCN8A (0.39) | SCN1ASCN8AKDM4ENR1I2SCN1B | |
| SCHEMBL20256322 | 0.73 | SCN8A (0.51) | SCN1ASCN8ANR1I2SCN1BSCN5A | |
| SCHEMBL19631580 | 0.73 | SCN8A (0.37) | SCN1ASCN8AKDM4ENR1I2SCN1B | |
| SCHEMBL29447368 | 0.73 | SCN8A (0.37) | SCN1ASCN8AKDM4ENR1I2SCN1B | |
| SCHEMBL19634332 | 0.73 | SCN8A (0.37) | SCN1ASCN8AKDM4ENR1I2SCN1B | |
| SCHEMBL20095879 | 0.71 | SCN9A (0.37) | KDM4E | |
| SCHEMBL19633964 | 0.70 | MAPT (0.34) | SCN8AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |