Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23070810 | 0.85 | NFE2L2 (0.41) | GAALMNAMAPTNFE2L2 | |
| SCHEMBL23070808 | 0.85 | NFE2L2 (0.41) | GAALMNAMAPTNFE2L2 | |
| SCHEMBL30608104 | 0.83 | AMY1A (0.34) | KDM4EAMY1ALMNAMAPTNFE2L2 | |
| SCHEMBL20256386 | 0.82 | GAA (0.36) | KDM4EGAANPSR1AMY1AHPGD | |
| SCHEMBL28094043 | 0.81 | BACE1 (0.39) | KDM4EGAAKMT2AMAPTMEN1 | |
| SCHEMBL28094044 | 0.81 | BACE1 (0.39) | KDM4EGAAKMT2AMAPTMEN1 | |
| SCHEMBL28338194 | 0.80 | AMY1A (0.46) | KDM4EGAAAMY1ALMNAKMT2A | |
| SCHEMBL28080217 | 0.79 | HPGD (0.40) | GAAHPGDTSHRLMNAKMT2A | |
| SCHEMBL14784357 | 0.77 | MAPT (0.36) | KDM4EGAANPSR1AMY1AHPGD | |
| SCHEMBL14784356 | 0.77 | MAPT (0.36) | KDM4EGAANPSR1AMY1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |