Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP2A13 | Q16696 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725885 | 0.85 | LMNA (0.51) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 | |
| SCHEMBL29738173 | 0.85 | LMNA (0.51) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 | |
| SCHEMBL2107499 | 0.81 | ALDH1A1 (0.96) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 | |
| SCHEMBL6803849 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBCYP2A13HTT | |
| SCHEMBL9417737 | 0.81 | SIGMAR1 (0.72) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 | |
| SCHEMBL29941203 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 | |
| SCHEMBL30341108 | 0.80 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBCYP2A13HTT | |
| SCHEMBL5738303 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 | |
| SCHEMBL3210628 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11467058 | 0.79 | SIGMAR1 (0.70) | ALDH1A1KDM4EPOLBCYP2A13SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |