Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634096 | 0.93 | MAPT (0.39) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL19634139 | 0.87 | MAPT (0.39) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL19614227 | 0.85 | SCN1A (0.43) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL19634012 | 0.83 | PDE4B (0.41) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL19631534 | 0.81 | SCN8A (0.41) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL19627661 | 0.80 | SCN1A (0.41) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL22590192 | 0.80 | GPR119 (0.44) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL19613246 | 0.80 | GPR119 (0.41) | MAPTGPR119PDE4BPDE4APDE4C | |
| SCHEMBL19634256 | 0.77 | P2RX3 (0.37) | MAPTPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL19631616 | 0.76 | PIK3CD (0.38) | MAPTGPR119PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |