Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716801 | 0.82 | PKM (0.60) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL19627389 | 0.79 | KMT2A (0.50) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL19629758 | 0.79 | KMT2A (0.57) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL8277082 | 0.78 | ALDH1A1 (0.59) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL6849915 | 0.78 | CA1 (0.58) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL19627384 | 0.76 | KMT2A (0.53) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL4476659 | 0.74 | KMT2A (0.63) | KMT2AMEN1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL417888 | 0.73 | KMT2A (0.58) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL425487 | 0.73 | KMT2A (0.58) | KMT2AMEN1TDP1SLC1A3SLC1A2 | |
| SCHEMBL30817621 | 0.72 | IDO1 (0.47) | KMT2AMEN1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017201155-A1 | lSOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2017-11-23 | — | — | WO | disclosed |