Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ACP1 | P24666 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457678 | 0.83 | TP53 (0.73) | LMNACYP2C9ACP1TP53L3MBTL1 | |
| SCHEMBL6297294 | 0.81 | LMNA (0.79) | KMT2AMEN1LMNACYP2C9ACP1 | |
| SCHEMBL4196236 | 0.81 | LMNA (0.78) | LMNACYP2C9ACP1TP53FBP1 | |
| SCHEMBL7770159 | 0.81 | LMNA (0.64) | KMT2AMEN1LMNACYP2C9ACP1 | |
| SCHEMBL6295746 | 0.80 | CA12 (0.69) | KMT2AMEN1LMNACYP2C9ACP1 | |
| SCHEMBL5186566 | 0.80 | LMNA (0.72) | KMT2AMEN1LMNACYP2C9ACP1 | |
| SCHEMBL4477902 | 0.79 | FBP1 (0.79) | KMT2AMEN1LMNAACP1FBP1 | |
| SCHEMBL19629758 | 0.78 | KMT2A (0.57) | KMT2AMEN1LMNATP53ALDH1A1 | |
| SCHEMBL9526415 | 0.77 | KMT2A (1.00) | KMT2AMEN1LMNATP53ALDH1A1 | |
| SCHEMBL27885 | 0.77 | LMNA (1.00) | KMT2AMEN1LMNACYP2C9ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067607-A2 | COMBINATIONS OF PDE4 INHIBITORS AND ANTIPSYCHOTICS FOR THE TREATMENT OF PSYCHOTIC DISORDERS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-05-28 | — | — | WO | disclosed |