Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | NAMPT | P43490 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634689 | 0.94 | MLYCD (0.54) | MLYCDHSD17B10LOXL2HDAC6HDAC1 | |
| SCHEMBL19634427 | 0.88 | HDAC3 (0.48) | MLYCDLOXL2HDAC6HDAC1HDAC3 | |
| SCHEMBL19634462 | 0.81 | HDAC1 (0.50) | MLYCDHSD17B10HDAC6HDAC1NAMPT | |
| SCHEMBL23471114 | 0.81 | LOXL2 (0.51) | MLYCDLOXL2HDAC6HDAC1NAMPT | |
| SCHEMBL12194867 | 0.80 | MLYCD (0.58) | MLYCDHSD17B10HDAC6HDAC1NAMPT | |
| SCHEMBL19634697 | 0.79 | LOXL2 (0.41) | MLYCDHSD17B10LOXL2HDAC6HDAC1 | |
| SCHEMBL18770116 | 0.79 | MLYCD (0.54) | MLYCDHSD17B10HDAC6HDAC1NAMPT | |
| SCHEMBL19634693 | 0.78 | LOXL2 (0.41) | MLYCDHSD17B10LOXL2HDAC6HDAC1 | |
| SCHEMBL23471110 | 0.78 | HDAC6 (0.53) | MLYCDHSD17B10HDAC6HDAC1NAMPT | |
| SCHEMBL9888697 | 0.77 | MLYCD (0.57) | MLYCDHSD17B10HDAC6HDAC1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |