Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634693 | 0.91 | LOXL2 (0.41) | LOXL2HSD17B10MLYCDALDH1A1GAA | |
| SCHEMBL23471020 | 0.84 | KMT2A (0.43) | HSD17B10MLYCDALDH1A1HDAC6HDAC1 | |
| SCHEMBL19634689 | 0.81 | MLYCD (0.54) | LOXL2HSD17B10MLYCDALDH1A1HDAC6 | |
| SCHEMBL19634396 | 0.81 | ERCC1 (0.38) | HSD17B10MLYCDALDH1A1GAAHDAC6 | |
| SCHEMBL19634456 | 0.81 | HDAC6 (0.44) | HSD17B10MLYCDALDH1A1GAAHDAC6 | |
| SCHEMBL19634420 | 0.79 | MLYCD (0.49) | LOXL2HSD17B10MLYCDHDAC6HDAC1 | |
| SCHEMBL23471017 | 0.78 | KMT2A (0.47) | HSD17B10MLYCDALDH1A1HDAC6HDAC1 | |
| SCHEMBL23471006 | 0.76 | HDAC3 (0.39) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21015838 | 0.75 | HDAC6 (0.48) | HSD17B10MLYCDALDH1A1HDAC6HDAC1 | |
| SCHEMBL19634408 | 0.75 | ERCC1 (0.40) | HSD17B10MLYCDALDH1A1HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |