Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634697 | 0.91 | LOXL2 (0.41) | LOXL2HDAC6HDAC3HDAC1HDAC4 | |
| SCHEMBL19634689 | 0.80 | MLYCD (0.54) | LOXL2HDAC6HDAC3HDAC1HDAC4 | |
| SCHEMBL23471107 | 0.80 | KMT2A (0.49) | HDAC6HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL19634427 | 0.79 | HDAC3 (0.48) | LOXL2HDAC6HDAC3HDAC1HDAC4 | |
| SCHEMBL19634420 | 0.78 | MLYCD (0.49) | LOXL2HDAC6HDAC3HDAC1HDAC4 | |
| SCHEMBL19634428 | 0.77 | ERCC1 (0.42) | HDAC6HDAC1ALDH1A1NPC1RAB9A | |
| SCHEMBL21015207 | 0.77 | HDAC6 (0.50) | HDAC6HDAC3HDAC1HDAC8MLYCD | |
| SCHEMBL23471020 | 0.74 | KMT2A (0.43) | HDAC6HDAC3HDAC1HDAC4HDAC2 | |
| SCHEMBL19634423 | 0.73 | MCHR1 (0.50) | LOXL2HDAC6HDAC3NCOR2ALDH1A1 | |
| SCHEMBL19634683 | 0.73 | HDAC6 (0.42) | LOXL2HDAC6HDAC3HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |