Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043354 | 0.86 | ATM (0.50) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL6043595 | 0.84 | GNAI3 (0.50) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL2732315 | 0.82 | ATM (0.50) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL11240 | 0.82 | L3MBTL1 (0.62) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL6044015 | 0.81 | TDP1 (0.50) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL6043600 | 0.80 | GNAI3 (0.50) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL10972319 | 0.80 | KMT2A (0.51) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL6043670 | 0.80 | ATM (0.48) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL5605136 | 0.80 | ATM (0.54) | ATMGNAI3GNAI1GNAO1L3MBTL1 | |
| SCHEMBL1302299 | 0.80 | SIGMAR1 (0.51) | ATMGNAI3GNAI1GNAO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |