Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634429 | 0.95 | LOXL2 (0.48) | LOXL2SPRHDAC3HDAC6HDAC4 | |
| SCHEMBL19634683 | 0.90 | HDAC6 (0.42) | LOXL2HDAC3HDAC6HDAC4HDAC1 | |
| SCHEMBL23471261 | 0.86 | ALDH1A1 (0.44) | SPRHDAC3HDAC6HDAC4HDAC1 | |
| SCHEMBL21015786 | 0.83 | HDAC6 (0.45) | SPRHDAC6HDAC1LMNANPC1 | |
| SCHEMBL19634806 | 0.83 | HSD17B10 (0.38) | SPRHDAC6HDAC1LMNANPC1 | |
| SCHEMBL23471018 | 0.81 | ALDH1A1 (0.48) | SPRHDAC3HDAC6HDAC4HDAC1 | |
| SCHEMBL23471251 | 0.78 | SPR (0.46) | SPRHDAC3HDAC6HDAC4HDAC1 | |
| SCHEMBL19634452 | 0.78 | HDAC6 (0.49) | SPRHDAC6HDAC1LMNANPC1 | |
| SCHEMBL19634698 | 0.78 | ERCC1 (0.41) | SPRHDAC6HDAC1LMNACYP2D6 | |
| SCHEMBL19634721 | 0.78 | LOXL2 (0.47) | LOXL2LMNATPSAB1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |