Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634806 | 0.96 | HSD17B10 (0.38) | ERCC1ERCC4HSD17B10SPRHDAC1 | |
| SCHEMBL23471018 | 0.87 | ALDH1A1 (0.48) | HSD17B10SPRHDAC1HDAC6ALDH1A1 | |
| SCHEMBL19634399 | 0.87 | ERCC1 (0.44) | ERCC1ERCC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL19634395 | 0.84 | MLYCD (0.46) | ERCC1ERCC4HSD17B10HDAC1HDAC6 | |
| SCHEMBL19634452 | 0.84 | HDAC6 (0.49) | HSD17B10SPRHDAC1HDAC6ALDH1A1 | |
| SCHEMBL19634741 | 0.83 | SPR (0.44) | ERCC1ERCC4HSD17B10SPRALDH1A1 | |
| SCHEMBL19634408 | 0.83 | ERCC1 (0.40) | ERCC1ERCC4HSD17B10HDAC1HDAC6 | |
| SCHEMBL23471261 | 0.83 | ALDH1A1 (0.44) | HSD17B10SPRHDAC1HDAC6ALDH1A1 | |
| SCHEMBL23471343 | 0.83 | ERCC1 (0.47) | ERCC1ERCC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL19634429 | 0.82 | LOXL2 (0.48) | HSD17B10SPRHDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |