Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21015318 | 0.85 | NR1H4 (0.51) | KDM1AMMP13HDAC6ROCK2HDAC2 | |
| SCHEMBL19634824 | 0.84 | HTT (0.52) | MMP13HDAC6ROCK2HDAC2HDAC8 | |
| SCHEMBL19634746 | 0.83 | MMP13 (0.49) | MMP13HDAC6ROCK2HDAC2HDAC8 | |
| SCHEMBL2828029 | 0.83 | F10 (0.57) | KDM1AMMP13HDAC6ROCK2HDAC2 | |
| SCHEMBL19634443 | 0.82 | HDAC1 (0.66) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL19634801 | 0.82 | SLC7A5 (0.58) | MMP13HDAC6ROCK2HDAC2HDAC8 | |
| SCHEMBL16380331 | 0.81 | ROCK2 (0.53) | MMP13HDAC6ROCK2HDAC2HDAC8 | |
| SCHEMBL18069355 | 0.81 | F10 (0.56) | HDAC6HDAC2HDAC8HDAC1HDAC3 | |
| SCHEMBL8646446 | 0.80 | HDAC1 (0.57) | MMP13HDAC6HDAC2HDAC8HDAC1 | |
| SCHEMBL19634728 | 0.79 | MMP13 (0.45) | MMP13HDAC6ROCK2HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |