Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 5/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291315 | 0.89 | PDPK1 (0.45) | PDPK1SMN1; SMN2HTTNCOA1NCOA3 | |
| Ribose (Furanose) SCHEMBL291402 | 0.81 | PDPK1 (0.61) | PDPK1HTTHSD17B10NPC1RAB9A | |
| SCHEMBL568026 | 0.76 | PDPK1 (0.46) | PDPK1ALDH1A1 | |
| SCHEMBL97672 | 0.76 | PDPK1 (0.46) | PDPK1ALDH1A1 | |
| SCHEMBL28125354 | 0.76 | MAPK1 (0.46) | PRKCA | |
| SCHEMBL28125353 | 0.76 | MAPK1 (0.46) | PRKCA | |
| SCHEMBL10325422 | 0.76 | MAPK1 (0.46) | PRKCA | |
| SCHEMBL10325424 | 0.76 | MAPK1 (0.46) | PRKCA | |
| SCHEMBL10325423 | 0.76 | MAPK1 (0.46) | PRKCA | |
| SCHEMBL1705332 | 0.72 | TLR4 (0.50) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658617-B2 | Salts of HIV inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-20110144050-A1 | SALTS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2011-06-16 | — | — | US | disclosed |
| US-20100093667-A1 | SALTS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093667-A1 | SALTS OF HIV INHIBITOR COMPOUNDS | SAMHD1, CCR5, ZC3HAV1 | PDPK1 2775/4885SMN1; SMN2 3989/4885HTT 1132/4885 |
| US-20110144050-A1 | SALTS OF HIV INHIBITOR COMPOUNDS | SAMHD1, CCR5, ZC3HAV1 | PDPK1 2775/4885SMN1; SMN2 3989/4885HTT 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.