Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 4/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906126 | 0.85 | PDPK1 (0.51) | PDPK1CDK2CDK1 | |
| Ribose (Furanose) SCHEMBL1531264 | 0.84 | HSD17B10 (0.40) | PDPK1CDK2PNPLMNAHSD17B10 | |
| Ribose (Furanose) SCHEMBL1682946 | 0.84 | HSD17B10 (0.40) | PDPK1CDK2PNPLMNAHSD17B10 | |
| Ribose (Furanose) SCHEMBL12542065 | 0.84 | HSD17B10 (0.40) | PDPK1CDK2PNPLMNAHSD17B10 | |
| SCHEMBL97672 | 0.82 | PDPK1 (0.46) | PDPK1CDK2CDK1CDC7DBF4 | |
| SCHEMBL568026 | 0.82 | PDPK1 (0.46) | PDPK1CDK2CDK1CDC7DBF4 | |
| Methylguanine SCHEMBL34851 | 0.82 | CDK1 (0.51) | CDK2CDK1 | |
| SCHEMBL291315 | 0.81 | PDPK1 (0.45) | PDPK1HSD17B10HTTNPC1RAB9A | |
| Ribose (Furanose) SCHEMBL17824409 | 0.81 | ADK (0.40) | CDK2CDC7DBF4PNPLMNA | |
| Adenine SCHEMBL38386 | 0.81 | PI4KA (0.58) | CDK2CDK1LMNAHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151635-A | Gene-modified NK cell lines transduced with genes encoding novel chimeric antigen receptors and uses thereof | 斯比根公司 | 2022-10-04 | — | — | CN | claimed |
| EP-3423473-A2 | VIRUS VECTORS EXPRESSING MULTIPLE EPITOPES OF TUMOR ASSOCIATED ANTIGENS FOR INDUCING ANTITUMOR IMMUNITY | New York University (US) | 2019-01-09 | — | — | EP | claimed |
| WO-2018161092-A1 | INDUCTION AND ENHANCEMENT OF ANTITUMOR IMMUNITY INVOLVING VIRUS VECTORS EXPRESSING MULTIPLE EPITOPES OF TUMOR ASSOCIATED ANTIGENS AND IMMUNE CHECKPOINT INHIBITORS OR PROTEINS | NEW YORK UNIVERSITY (US) | 2018-09-07 | — | — | WO | claimed |
| US-20180000912-A1 | Virus Vectors Expressing Multiple Epitopes of Tumor Associated Antigens For Inducing Antitumor Immunity | NEW YORK UNIVERSITY | 2018-01-04 | — | — | US | claimed |
| EP-2308885-B1 | Novel compounds and methods for therapy | GILEAD SCIENCES INC (US) | 2014-11-19 | — | — | EP | claimed |
| EP-2245037-B1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | GILEAD SCIENCES INC (US) | 2014-06-18 | — | — | EP | claimed |
| US-8071740-B2 | Isolated polynucleotide sequences; controlling neuvasculization ; cell growth factor | VASCULAR BIOGENICS LTD. (IL) | 2011-12-06 | — | — | US | claimed |
| US-20110257250-A1 | Treating Insulin Secreting Cells | BRUNICARDI F CHARLES | 2011-10-20 | — | — | US | claimed |
| EP-2308885-A2 | Novel compounds and methods for therapy | Gilead Sciences, Inc. (US) | 2011-04-13 | — | — | EP | claimed |
| US-7923243-B2 | Expression vector comprising glucose regulated protein 78 (grp78) stress-responsive promoter and endoplasmic reticulum stress elements for use in tissue specific heterologous gene expression for treatment and prevention of cell proliferative and inflammatory disorders | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-04-12 | — | — | US | claimed |
| WO-2002061103-A1 | METHOD FOR OBTAINING PACKAGING CELLS PRODUCING RETROVIRUS BY ELIMINATING CELLS LIABLE TO BE INFECTED BY THE RETROVIRUS PRODUCED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2002-08-08 | — | — | WO | claimed |
| WO-2001000791-A9 | STRESS-RESPONSIVE INDUCTION OF A THERAPEUTIC AGENT AND METHODS OF USE | UNIV SOUTHERN CALIFORNIA (US) | 2002-07-25 | — | — | WO | claimed |
| EP-1194527-A1 | STRESS-RESPONSIVE INDUCTION OF A THERAPEUTIC AGENT AND METHODS OF USE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2002-04-10 | — | — | EP | claimed |
| US-6217860-B1 | SUPPLYING ADENOVIRAL VECTOR INTO TUMOR | BAYLOR COLLEGE OF MEDICINE | 2001-04-17 | — | — | US | claimed |
| WO-2001000791-A1 | STRESS-RESPONSIVE INDUCTION OF A THERAPEUTIC AGENT AND METHODS OF USE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2001-01-04 | — | — | WO | claimed |
| US-6066624-A | TOGETHER WITH PRODRUG | BAYLOR COLLEGE OF MEDICINE (US) | 2000-05-23 | — | — | US | claimed |
| EP-0719147-A4 | GENE THERAPY FOR SOLID TUMORS, PAPILLOMAS AND WARTS | BAYLOR COLLEGE MEDICINE (US) | 1998-09-16 | — | — | EP | claimed |
| US-5631236-A | Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk | BAYLOR COLLEGE OF MEDICINE (US) | 1997-05-20 | — | — | US | claimed |
| EP-0719147-A1 | GENE THERAPY FOR SOLID TUMORS, PAPILLOMAS AND WARTS | BAYLOR COLLEGE OF MEDICINE (US) | 1996-07-03 | — | — | EP | claimed |
| WO-1995005835-A1 | GENE THERAPY FOR SOLID TUMORS, PAPILLOMAS AND WARTS | BAYLOR COLLEGE OF MEDICINE (US) | 1995-03-02 | — | — | WO | claimed |