Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635179 | 0.89 | KDM4C (0.34) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL19635446 | 0.76 | ADORA3 (0.37) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL20524326 | 0.75 | KDM4C (0.45) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL19615379 | 0.73 | KDM4C (0.39) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL15701737 | 0.69 | KDM4C (0.40) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL5429878 | 0.69 | KDM4C (0.49) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL29749639 | 0.68 | NPC1 (0.50) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL28796337 | 0.68 | NPC1 (0.50) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL24669516 | 0.68 | KDM4C (0.51) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL21436952 | 0.68 | MEN1 (0.47) | KDM4CL3MBTL1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |