SCHEMBL28113723

SCHEMBL28113723

Nc1ccc(S(=O)(=O)NCc2cccc3ccccc23)cc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.63
PRMT1 Q99873 2/20 0.52
HTR6 P50406 1/20 0.51
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA9 Q16790 3/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP3A4 P08684 1/20 0.47
NQO2 P16083 1/20 0.46
GHSR Q92847 1/20 0.45
GAA P10253 1/20 0.45
CYP2C19 P33261 1/20 0.45
GUSB P08236 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4770153 0.88 CA2 (0.66) CA2CA12CA1CA9CA4
SCHEMBL19636715 0.85 MEN1 (0.68) CA2CA12CA9MEN1KMT2A
SCHEMBL4874695 0.81 CYP19A1 (0.61) CA2CA12CA1CA9MEN1
SCHEMBL28113175 0.79 POLB (0.68) CA2PRMT1CA12CA1CA9
SCHEMBL28113720 0.79 CA12 (0.56) CA2PRMT1CA12CA1CA9
SCHEMBL29258799 0.79 LMNA (0.60) CA2PRMT1CA12CA1CA9
SCHEMBL4872425 0.79 CA2 (0.53) CA2CA12CA1CA9CA4
SCHEMBL4270510 0.78 CA2 (1.00) CA2CA12CA1CA9CA4
SCHEMBL4449107 0.77 NSD2 (0.68) CA2CYP3A4CYP2C19
SCHEMBL4478162 0.77 CA2 (0.56) CA2CA12CA1CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146358-B Method for synthesizing amino- (N-alkyl) benzene sulfonamide 南京理工大学 2018-01-23 CN disclosed
CN-106146358-A Method for synthesizing amino- (N-alkyl) benzene sulfonamide 南京理工大学 2016-11-23 CN disclosed