Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023132 | 0.83 | NR1H2 (0.41) | KMT2AMEN1BCHEMAPTPKM | |
| SCHEMBL7014583 | 0.80 | CA12 (0.42) | KMT2AMEN1MAPTESR2ALDH1A1 | |
| SCHEMBL11911366 | 0.79 | GPR119 (0.39) | GPR119KMT2AMEN1BCHEMAPT | |
| SCHEMBL7528678 | 0.79 | ESR2 (0.40) | GPR119KMT2AMEN1BCHEMAPT | |
| SCHEMBL7370834 | 0.79 | MEN1 (0.34) | GPR119KMT2AMEN1BCHEBUB1 | |
| SCHEMBL12593934 | 0.77 | NR1H2 (0.41) | GPR119KMT2AMEN1BCHEBUB1 | |
| SCHEMBL1018306 | 0.77 | BCHE (0.38) | GPR119KMT2AMEN1BCHEMAPT | |
| SCHEMBL28581988 | 0.77 | BCHE (0.38) | GPR119KMT2AMEN1BCHEMAPT | |
| SCHEMBL20033881 | 0.77 | BCHE (0.38) | GPR119KMT2AMEN1BCHEMAPT | |
| Hydrochloric Acid SCHEMBL28584468 | 0.76 | BCHE (0.37) | GPR119KMT2AMEN1BCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105924379-A | Preparation method of 1-BOC-3-hydroxymethyl pyrrolidine | 苏州艾缇克药物化学有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-119823103-A | Polycyclic derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| EP-3248980-B1 | JAK INHIBITOR | WUXI FORTUNE PHARMACEUTICAL CO LTD (CN) | 2023-09-06 | — | — | EP | disclosed |
| CN-111518096-B | Janus kinase JAK family inhibitor and preparation and application thereof | 江苏威凯尔医药科技有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-108349977-B | JAK inhibitors | 无锡福祈制药有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-111518096-A | Janus kinase JAK family inhibitor and preparation and application thereof | 江苏威凯尔医药科技有限公司 | 2020-08-11 | — | — | CN | disclosed |
| US-10617690-B2 | JAK inhibitor | Wuxi Fortune Pharmaceutical Co., Ltd (CN) | 2020-04-14 | — | — | US | disclosed |
| CN-108349977-A | Jak inhibitor | 无锡福祈制药有限公司 | 2018-07-31 | — | — | CN | disclosed |
| US-20170360794-A1 | JAK INHIBITOR | Wuxi Fortune Pharmaceutical Co., Ltd (CN) | 2017-12-21 | — | — | US | disclosed |
| EP-3248980-A1 | JAK INHIBITOR | Wuxi Fortune Pharmaceutical Co., Ltd (CN) | 2017-11-29 | — | — | EP | disclosed |
| CN-105924379-A | Preparation method of 1-BOC-3-hydroxymethyl pyrrolidine | 苏州艾缇克药物化学有限公司 | 2016-09-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360794-A1 | JAK INHIBITOR | JAK2, JAK1, JAK3 | GPR119 1493/4885KMT2A 665/4885MEN1 2985/4885 |
| US-10617690-B2 | JAK inhibitor | JAK2, JAK1, JAK3 | GPR119 1493/4885KMT2A 665/4885MEN1 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.