SCHEMBL19638404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL824913	0.81	CYP3A4 (0.48)	ALDH1A1MAOBMAOAFTOHSD17B10
	SCHEMBL18803668	0.78	ALDH1A1 (0.52)	ALDH1A1L3MBTL1MAOBMAOAHSD17B10
	SCHEMBL22115937	0.78	MAOA (0.48)	ALDH1A1L3MBTL1MAOBMAOAFTO
	SCHEMBL28143837	0.77	MAOA (0.47)	MAOBMAOAFTOKCNA3HPGD
	SCHEMBL16623899	0.76	ALDH1A1 (0.77)	ALDH1A1L3MBTL1HSD17B10HPGDSMN1; SMN2
	SCHEMBL2143620	0.76	MAOB (0.45)	ALDH1A1MAOBMAOAFTOHSD17B10
	SCHEMBL28876423	0.73	MAOA (0.39)	ALDH1A1MAOBMAOAFTOKCNA3
	SCHEMBL28229774	0.73	PTPN1 (0.45)	ALDH1A1MAOBMAOAFTOKCNA3
	SCHEMBL28275978	0.73	MAOA (0.43)	ALDH1A1L3MBTL1MAOBMAOAFTO
	Oxalic Acid SCHEMBL16467215	0.72	MAOB (0.41)	ALDH1A1MAOBMAOAFTOHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.