Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 8/20 | 0.49 |
| ▸ | SENP5 | Q96HI0 | 6/20 | 0.48 |
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.44 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639347 | 0.89 | NAMPT (0.52) | NAMPTHDAC1RAB9AKMT2ANPC1 | |
| SCHEMBL27113168 | 0.86 | SENP5 (0.43) | SENP1SENP5SENP2RAB9AKMT2A | |
| SCHEMBL22227454 | 0.85 | NR1H4 (0.51) | HDAC1RAB9ANR1H4NPFFR1NPFFR2 | |
| SCHEMBL27113174 | 0.85 | AURKA (0.43) | SENP1NAMPTMAPTSMN1; SMN2CCKBR | |
| SCHEMBL6679118 | 0.84 | SENP1 (0.49) | SENP1SENP5SENP2RAB9ANR1H4 | |
| SCHEMBL19651943 | 0.84 | CA1 (0.51) | NAMPTHDAC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL17902822 | 0.84 | CA1 (0.51) | NAMPTHDAC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL6679114 | 0.83 | SENP1 (0.48) | SENP1SENP5SENP2HDAC1NR1H4 | |
| SCHEMBL2248369 | 0.82 | AURKA (0.41) | NAMPTHDAC1NPFFR1NPFFR2MAPT | |
| SCHEMBL10160157 | 0.82 | SENP1 (0.55) | SENP1SENP5SENP2NAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | SENP1 2986/4885SENP5 1658/4885SENP2 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.