Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831106 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16986779 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL18264410 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL18877220 | 1.00 | LMNA (0.50) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL92729 | 0.95 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL1668363 | 0.95 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL1964137 | 0.95 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL2297555 | 0.95 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL19741239 | 0.95 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL4996629 | 0.95 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150009-A | POLYOL WITH FOUR OR MORE HYDROXYL GROUPS | ABTEC CHEMICAL COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| WO-2024026062-A1 | POLYSILOXANE FOAM COMPOSITIONS AND METHODS RELATED THERETO | NUSIL TECHNOLOGY LLC (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2023111405-A1 | METHOD FOR PREPARING SILICONE FOAM | ELKEM SILICONES FRANCE SAS (FR) | 2023-06-22 | — | — | WO | disclosed |
| EP-2917030-B1 | FLEXIBLE HEAT SHIELD WITH SILICONE ELASTOMER AND A TOPCOAT FOR INFLATIBLE SAFETY DEVICES | DOW SILICONES CORP (US) | 2022-04-27 | — | — | EP | disclosed |
| US-11014952-B2 | Stable hydrolysis-resistant synthetic polyribosylribitolphosphate derivatives as vaccines against Haemophilus influenzae type b | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-05-25 | — | — | US | disclosed |
| US-10392743-B2 | Flexible heat shield with silicone elastomer and a topcoat for inflatable safety devices | DOW SILICONES CORPORATION (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190153015-A1 | STABLE HYDROLYSIS-RESISTANT SYNTHETIC POLYRIBOSYLRIBITOLPHOSPHATE DERIVATIVES AS VACCINES AGAINST HAEMOPHILUS INFLUENZAE TYPE B | VAXXILON AG (CH) | 2019-05-23 | — | — | US | disclosed |
| US-20170218129-A1 | METHOD FOR PRODUCING LIQUID HIGH-PURITY SUGAR DERIVATIVE-MODIFIED SILICONE OR COMPOSITION THEREOF | DOW TORAY CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| US-9480630-B2 | Co-modified organopolysiloxane, emulsifier for water-in-oil emulsion, external use preparation, and cosmetic composition using the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-11-01 | — | — | US | disclosed |
| US-9475828-B2 | Organopolysiloxane and use thereof as surfactant, powder treatment agent, thickening agent of oil-based raw material or gelling agent. gel and emulsion compositions, as well as, preparations for external use and cosmetics comprising the same | DOW CORNING TORAY CO., LTD. (JP) | 2016-10-25 | — | — | US | disclosed |
| US-20140187649-A1 | Novel Liquid Organo Polysiloxane And Use Therefor | Dow Coming Toray Co., Ltd (JP) | 2014-07-03 | — | — | US | disclosed |
| WO-2014075036-A1 | FLEXIBLE HEAT SHIELD WITH SILICONE ELASTOMER AND A TOPCOAT FOR INFLATIBLE SAFETY DEVICES | DOW CORNING CORPORATION (US) | 2014-05-15 | — | — | WO | disclosed |
| WO-2014008322-A1 | FLEXIBLE HEAT SHIELD WITH SILICONE FOAM FOR INFLATABLE SAFETY DEVICES | DOW CORNING CORPORATION (US) | 2014-01-09 | — | — | WO | disclosed |
| US-20130210930-A1 | ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME | DOW CORNING TORAY CO., LTD. (JP) | 2013-08-15 | — | — | US | disclosed |
| US-20130177516-A1 | Cosmetic For Hair Containing Sugar Alcohol-Modified Silicone | DOW CORNING TORAY CO., LTD. (JP) | 2013-07-11 | — | — | US | disclosed |
| EP-1149125-A1 | FLAME RETARDANT SILICONE FOAMS | DOW CORNING CORPORATION (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000046282-A1 | FLAME RETARDANT SILICONE FOAMS | DOW CORNING CORPORATION (US) | 2000-08-10 | — | — | WO | disclosed |
| US-6084002-A | Flame retardant silicone foams | DOW CORNING CORPORATION (US) | 2000-07-04 | — | — | US | disclosed |
| US-4871781-A | ALCOHOL BLOWING AGENT | WACKER-CHEMIE GMBH (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4150009-A | POLYOL WITH FOUR OR MORE HYDROXYL GROUPS | ABTEC CHEMICAL COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170218129-A1 | METHOD FOR PRODUCING LIQUID HIGH-PURITY SUGAR DERIVATIVE-MODIFIED SILICONE OR COMPOSITION THEREOF | SORD, GYS1, CD44 | LMNA 954/4885L3MBTL1 1486/4885TDP1 2988/4885 |
| US-11014952-B2 | Stable hydrolysis-resistant synthetic polyribosylribitolphosphate derivatives as vaccines against Haemophilus influenzae type b | ENTPD5, RPIA, RNASEL | LMNA 1305/4885L3MBTL1 2254/4885TDP1 1255/4885 |
| US-20190153015-A1 | STABLE HYDROLYSIS-RESISTANT SYNTHETIC POLYRIBOSYLRIBITOLPHOSPHATE DERIVATIVES AS VACCINES AGAINST HAEMOPHILUS INFLUENZAE TYPE B | ENTPD5, RPIA, RNASEL | LMNA 1305/4885L3MBTL1 2254/4885TDP1 1255/4885 |
| US-20130210930-A1 | ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME | DDOST, RPN1, RPN2 | LMNA 633/4885L3MBTL1 3339/4885TDP1 4326/4885 |
| US-20140187649-A1 | Novel Liquid Organo Polysiloxane And Use Therefor | OR51E2, SORD, CUTA | LMNA 4007/4885L3MBTL1 2133/4885TDP1 3790/4885 |
| US-20130177516-A1 | Cosmetic For Hair Containing Sugar Alcohol-Modified Silicone | DPM1, FSCN1, CD44 | LMNA 873/4885L3MBTL1 4246/4885TDP1 4738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.