SCHEMBL19641808

SCHEMBL19641808

Cn1c(C(F)(F)F)cc(=O)n(-c2nc(Oc3ccccc3OCC(=O)NS(C)(=O)=O)c(Cl)cc2F)c1=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 15/20 0.36
THRB P10828 1/20 0.34
CXCL8 P10145 1/20 0.34
POLB P06746 1/20 0.34
MGLL Q99685 1/20 0.34
PPARG P37231 1/20 0.33
SCN5A Q14524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435268 1.00 SCN9A (0.36) SCN9ATHRBCXCL8POLBMGLL
SCHEMBL20723425 0.92 SCN9A (0.38) SCN9ASCN5A
SCHEMBL29577025 0.92 SCN9A (0.38) SCN9ASCN5A
SCHEMBL31426399 0.90 SCN9A (0.33) SCN9AMGLLSCN5A
SCHEMBL23616634 0.89 SCN9A (0.32) SCN9ATHRBPOLB
SCHEMBL23616636 0.88 THRB (0.35) THRBPOLB
SCHEMBL29577052 0.88 LMNA (0.34) THRBPOLB
SCHEMBL20723424 0.88 LMNA (0.34) THRBPOLB
SCHEMBL29435276 0.88 PKM (0.36) THRBPOLB
SCHEMBL19641759 0.88 PKM (0.36) THRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2026-01-08 US claimed
US-12123010-B2 Plants having increased tolerance to herbicides BASF SE (DE) 2024-10-22 US claimed
WO-2024012905-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS BASF SE (DE) 2024-01-18 WO claimed
US-20220079157-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN CORN CULTURES BASF SE (DE) 2022-03-17 US claimed
US-20200367501-A1 Herbicidal mixtures comprising L-glufosinate and their use in soybean cultures BASF SE (DE) 2020-11-26 US claimed
US-20200359631-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE OR ITS SALT AND AT LEAST ONE PROTOPORPHYRINOGEN-IX OXIDASE INHIBITOR BASF SE (DE) 2020-11-19 US claimed
US-20200359630-A1 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN CORN CULTURES BASF SE (DE) 2020-11-19 US claimed
WO-2019030095-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN CORN CULTURES BASF SE (DE) 2019-02-14 WO claimed
WO-2019030091-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN COTTON CULTURES BASF SE (DE) 2019-02-14 WO claimed
WO-2019030086-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN CANOLA CULTURES BASF SE (DE) 2019-02-14 WO claimed
WO-2019030097-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN SOYBEAN CULTURES BASF SE (DE) 2019-02-14 WO claimed
US-12617803-B2 Condensed isoxazoline derivatives and their use as herbicides BASF SE (DE) 2026-05-05 US disclosed
US-12612394-B2 Herbicidal malonamides BASF SE (DE) 2026-04-28 US disclosed
EP-4696682-A1 HERBICIDAL THIOCARBAMATES CARRYING AN ETHER-SUBSTITUTED PHENYL RING BASF SE (DE) 2026-02-18 EP disclosed
EP-4696681-A1 HERBICIDAL THIOCARBAMATES CARRYING AN ISOXAZOLIN-SUBSTITUTED PHENYL RING BASF SE (DE) 2026-02-18 EP disclosed
WO-2019030097-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN SOYBEAN CULTURES BASF SE (DE) 2019-02-14 WO disclosed
WO-2019030091-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN COTTON CULTURES BASF SE (DE) 2019-02-14 WO disclosed
WO-2019030095-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN CORN CULTURES BASF SE (DE) 2019-02-14 WO disclosed
WO-2019030086-A2 HERBICIDAL MIXTURES COMPRISING L-GLUFOSINATE AND THEIR USE IN CANOLA CULTURES BASF SE (DE) 2019-02-14 WO disclosed
WO-2017202768-A1 HERBICIDAL URACILPYRID BASF SE (DE) 2017-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617803-B2 Condensed isoxazoline derivatives and their use as herbicides CBR3, CBR1, GLRA3 SCN9A 2612/4885THRB 665/4885CXCL8 3085/4885
US-12612394-B2 Herbicidal malonamides CBR3, DDT, HACL2 SCN9A 181/4885THRB 2705/4885CXCL8 4385/4885
US-20260007133-A1 HERBICIDAL COMPOSITION COMPRISING AZINE COMPOUNDS CBR3, CBR1, DDT SCN9A 1749/4885THRB 1359/4885CXCL8 3065/4885
US-12123010-B2 Plants having increased tolerance to herbicides PPOX, PNPO, PAOX SCN9A 3781/4885THRB 3035/4885CXCL8 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.