Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963774 | 0.89 | ALDH1A1 (0.34) | PDE10ABACE1 | |
| SCHEMBL1963805 | 0.89 | BACE1 (0.35) | PDE10ABACE1 | |
| SCHEMBL25911523 | 0.80 | ESR1 (0.42) | — | |
| SCHEMBL31026244 | 0.74 | BACE1 (0.35) | BACE1 | |
| SCHEMBL2166816 | 0.74 | CA9 (0.38) | PDE10ABACE1 | |
| SCHEMBL25251144 | 0.73 | DGAT1 (0.35) | BACE1 | |
| SCHEMBL24619702 | 0.73 | CCR1 (0.41) | — | |
| SCHEMBL2170889 | 0.73 | BACE1 (0.36) | BACE1 | |
| SCHEMBL31284234 | 0.71 | NQO2 (0.34) | — | |
| SCHEMBL20660798 | 0.71 | BACE1 (0.33) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334677-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010022076-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-02-25 | — | — | WO | disclosed |