Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963805 | 0.82 | BACE1 (0.35) | — | |
| SCHEMBL1964184 | 0.80 | PDE10A (0.30) | — | |
| SCHEMBL17434591 | 0.80 | HSD17B10 (0.41) | ESR1ESR2PLAU | |
| SCHEMBL2170889 | 0.77 | BACE1 (0.36) | GAA | |
| SCHEMBL31623199 | 0.73 | POLB (0.34) | GAA | |
| SCHEMBL27364124 | 0.73 | FPR2 (0.39) | PLAUTAAR1 | |
| SCHEMBL1289669 | 0.71 | LMNA (0.39) | GAA | |
| SCHEMBL1967396 | 0.69 | SLC40A1 (0.42) | PLAUGAA | |
| SCHEMBL31683661 | 0.69 | SLC40A1 (0.42) | PLAUGAA | |
| SCHEMBL31026244 | 0.69 | BACE1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2024049976-A1 | N-METHYL-4-(QUINOLIN-2-YL)PYRIDIN-2-AMINE COMPOUNDS | ABBVIE INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |