SCHEMBL19642850

SCHEMBL19642850

CSCn1cnc2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.63
▸ CYP11B1 P15538 5/20 0.56
▸ CYP11B2 P19099 5/20 0.56
▸ TNF P01375 1/20 0.56
▸ HTT P42858 4/20 0.54
▸ LMNA P02545 4/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ EGLN3 Q9H6Z9 1/20 0.54
▸ APAF1 O14727 1/20 0.54
▸ FDPS P14324 2/20 0.53
▸ MAPK1 P28482 2/20 0.51
▸ PKM P14618 1/20 0.51
▸ GGPS1 O95749 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ NPC1 O15118 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3079522 0.85 TDP1 (0.68) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL32660136 0.85 TDP1 (0.74) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL3065318 0.85 TDP1 (0.74) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL13870066 0.82 TDP1 (0.70) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL226221 0.79 TDP1 (0.70) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL3862944 0.79 TDP1 (0.70) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL30038122 0.79 TDP1 (0.70) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL8413094 0.78 APAF1 (0.55) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL6442808 0.78 TDP1 (1.00) TDP1CYP11B1CYP11B2TNFHTT
SCHEMBL6794361 0.78 TDP1 (0.76) TDP1CYP11B1CYP11B2TNFHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518933-B2 Precursor based method of synthesis and fabrication of hybrid lighting phosphors with high quantum efficiency, and significantly enhanced thermal and photostability RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-12-06 — — US disclosed
US-11518933-B2 Precursor based method of synthesis and fabrication of hybrid lighting phosphors with high quantum efficiency, and significantly enhanced thermal and photostability RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-12-06 — — US disclosed
EP-3464298-B1 PRECURSOR BASED METHOD OF SYNTHESIS AND FABRICATION OF HYBRID LIGHTING PHOSPHORS WITH HIGH QUANTUM EFFICIENCY, AND SIGNIFICANTLY ENHANCED THERMAL AND PHOTOSTABILITY UNIV RUTGERS (US) 2022-07-06 — — EP disclosed
EP-3464298-B1 PRECURSOR BASED METHOD OF SYNTHESIS AND FABRICATION OF HYBRID LIGHTING PHOSPHORS WITH HIGH QUANTUM EFFICIENCY, AND SIGNIFICANTLY ENHANCED THERMAL AND PHOTOSTABILITY UNIV RUTGERS (US) 2022-07-06 — — EP disclosed
US-20190292450-A1 Precursor Based Method of Synthesis and Fabrication of Hybrid Lighting Phosphors with High Quantum Efficiency, and Significantly Enhanced Thermal and Photostability NATIONAL SCIENCE FOUNDATION 2019-09-26 — — US disclosed
US-20190292450-A1 Precursor Based Method of Synthesis and Fabrication of Hybrid Lighting Phosphors with High Quantum Efficiency, and Significantly Enhanced Thermal and Photostability NATIONAL SCIENCE FOUNDATION 2019-09-26 — — US disclosed
EP-3464298-A1 PRECURSOR BASED METHOD OF SYNTHESIS AND FABRICATION OF HYBRID LIGHTING PHOSPHORS WITH HIGH QUANTUM EFFICIENCY, AND SIGNIFICANTLY ENHANCED THERMAL AND PHOTOSTABILITY Rutgers, The State University of New Jersey (US) 2019-04-10 — — EP disclosed
WO-2017205092-A1 PRECURSOR BASED METHOD OF SYNTHESIS AND FABRICATION OF HYBRID LIGHTING PHOSPHORS WITH HIGH QUANTUM EFFICIENCY, AND SIGNIFICANTLY ENHANCED THERMAL AND PHOTOSTABILITY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-11-30 — — WO disclosed
WO-2017205092-A1 PRECURSOR BASED METHOD OF SYNTHESIS AND FABRICATION OF HYBRID LIGHTING PHOSPHORS WITH HIGH QUANTUM EFFICIENCY, AND SIGNIFICANTLY ENHANCED THERMAL AND PHOTOSTABILITY RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-11-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11518933-B2 Precursor based method of synthesis and fabrication of hybrid lighting phosphors with high quantum efficiency, and significantly enhanced thermal and photostability DCX, ZKSCAN2, CAD TDP1 4193/4885CYP11B1 4772/4885CYP11B2 4657/4885
US-20190292450-A1 Precursor Based Method of Synthesis and Fabrication of Hybrid Lighting Phosphors with High Quantum Efficiency, and Significantly Enhanced Thermal and Photostability DCX, ZKSCAN2, CAD TDP1 4193/4885CYP11B1 4772/4885CYP11B2 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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