Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644457 | 0.77 | DNM1 (0.34) | MAPK1HTTKMT2ADNM1 | |
| SCHEMBL19643687 | 0.73 | TSHR (0.41) | CYP2D6 | |
| SCHEMBL19644047 | 0.71 | CYP2D6 (0.41) | CYP2D6KMT2A | |
| SCHEMBL28640892 | 0.71 | LMNA (0.46) | LMNACYP3A4CYP2D6MAPK1THPO | |
| SCHEMBL22301651 | 0.71 | PSMD14 (0.44) | LMNACYP3A4CYP2D6MAPK1THPO | |
| Bretylium SCHEMBL29688247 | 0.69 | LMNA (0.65) | LMNACYP3A4CYP2D6MAPK1THPO | |
| Bretylium SCHEMBL542733 | 0.69 | LMNA (0.65) | LMNACYP3A4CYP2D6MAPK1THPO | |
| Bretylium SCHEMBL15438 | 0.69 | LMNA (0.65) | LMNACYP3A4CYP2D6MAPK1THPO | |
| Bromide SCHEMBL22301649 | 0.69 | DNM1 (0.45) | LMNACYP3A4CYP2D6MAPK1THPO | |
| Bretylium SCHEMBL16398024 | 0.68 | LMNA (0.63) | LMNACYP3A4CYP2D6MAPK1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205041-A1 | HIGH CHARGE DENSITY METALLOPHOSPHATE MOLECULAR SIEVES | UOP LLC (US) | 2017-11-30 | — | — | WO | claimed |
| CN-108495816-B | High charge density metalloaluminophosphate molecular sieves | 环球油品公司 | 2022-05-03 | — | — | CN | disclosed |