Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 2/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644595 | 0.92 | RNASEL (0.33) | RNASELP2RX1P2RX3P2RX4 | |
| SCHEMBL19644600 | 0.84 | POLRMT (0.36) | RNASELP2RX1P2RX3P2RX4 | |
| SCHEMBL19779073 | 0.76 | POLRMT (0.50) | RNASEL | |
| SCHEMBL17453495 | 0.76 | P2RY2 (0.38) | RNASELP2RX1P2RX3P2RX4IMPDH2 | |
| SCHEMBL17453498 | 0.74 | P2RY2 (0.41) | RNASELP2RX1P2RX3IMPDH2 | |
| SCHEMBL19644566 | 0.74 | POLRMT (0.36) | RNASELP2RX1P2RX3P2RX4 | |
| SCHEMBL19644575 | 0.73 | HIF1A (0.32) | — | |
| SCHEMBL19644602 | 0.72 | P2RY1 (0.40) | RNASELP2RX1P2RX3P2RX4IMPDH2 | |
| SCHEMBL21880479 | 0.71 | POLRMT (0.35) | RNASELP2RX1P2RX3P2RX4 | |
| SCHEMBL19962266 | 0.70 | P2RY2 (0.39) | RNASELP2RX1P2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828388-B2 | Thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-D]pyrimidines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2017-11-28 | — | — | US | disclosed |