Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352301 | 0.84 | ALDH1A1 (0.51) | SMN1; SMN2LMNAALDH1A1CASP1HTT | |
| SCHEMBL31418693 | 0.84 | ALDH1A1 (0.51) | SMN1; SMN2LMNAALDH1A1CASP1HTT | |
| SCHEMBL30442090 | 0.84 | ALDH1A1 (0.51) | SMN1; SMN2LMNAALDH1A1CASP1HTT | |
| SCHEMBL1412214 | 0.82 | TPSAB1 (0.50) | SMN1; SMN2LMNAALDH1A1CCNE1CDK2 | |
| SCHEMBL20785502 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2LMNAALDH1A1CASP1HTT | |
| SCHEMBL22043005 | 0.77 | HDAC2 (0.45) | SMN1; SMN2LMNAALDH1A1HTTMEN1 | |
| SCHEMBL5057001 | 0.77 | HTT (0.52) | SMN1; SMN2LMNAALDH1A1CASP1HTT | |
| SCHEMBL23451324 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1GAAHTT | |
| SCHEMBL10177562 | 0.76 | HTT (0.48) | SMN1; SMN2LMNAHTT | |
| SCHEMBL25333732 | 0.76 | LMNA (0.63) | SMN1; SMN2LMNAGAAHTTTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879041-B2 | Saccharide dendritic cluster compounds as inhibitors of BACE-1 | VICTORIA LINK LIMITED (NZ) | 2018-01-30 | — | — | US | disclosed |
| US-9828341-B2 | Dendritic core compounds | VICTORIA LINK LIMITED (NZ) | 2017-11-28 | — | — | US | disclosed |