SCHEMBL5352301

SCHEMBL5352301

O=C(CNC(=O)OCc1ccccc1)NCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
TPSAB1 Q15661 2/20 0.47
TPSD1 Q9BZJ3 2/20 0.47
TPSG1 Q9NRR2 2/20 0.47
KDM1A O60341 1/20 0.45
RCOR1 Q9UKL0 1/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CASP1 P29466 1/20 0.44
ATM Q13315 1/20 0.44
PRSS1 P07477 1/20 0.44
MCHR1 Q99705 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 2/20 0.43
OPRK1 P41145 1/20 0.43
PREP P48147 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30442090 1.00 ALDH1A1 (0.51) ALDH1A1TPSAB1TPSD1TPSG1KDM1A
SCHEMBL31418693 1.00 ALDH1A1 (0.51) ALDH1A1TPSAB1TPSD1TPSG1KDM1A
SCHEMBL1412214 0.95 TPSAB1 (0.50) ALDH1A1TPSAB1TPSD1TPSG1LMNA
SCHEMBL20785502 0.92 ALDH1A1 (0.47) ALDH1A1TPSAB1TPSD1TPSG1KDM1A
SCHEMBL19645166 0.84 SMN1; SMN2 (0.40) ALDH1A1TPSAB1TPSD1TPSG1LMNA
SCHEMBL10703021 0.84 ALDH1A1 (0.47) ALDH1A1TPSAB1TPSD1TPSG1KDM1A
SCHEMBL9044348 0.83 ALDH1A1 (0.47) ALDH1A1CASP1
SCHEMBL12934822 0.83 ALDH1A1 (0.47) ALDH1A1TPSAB1TPSD1TPSG1KDM1A
SCHEMBL6420313 0.83 GAA (0.58) TPSAB1TPSD1TPSG1LMNASMN1; SMN2
SCHEMBL10633732 0.81 CYP1A2 (0.52) TPSAB1CASP1PRSS1PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714956-A2 IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE Daiichi Sankyo Company, Limited (JP) 2026-03-25 EP disclosed
US-12545716-B2 Immunoconjugates and methods IMMUNOME, INC. (US) 2026-02-10 US disclosed
US-12503489-B2 Method for producing antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-12-23 US disclosed
EP-3677589-B1 IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO CO LTD (JP) 2025-11-26 EP disclosed
US-12280121-B2 Immunoconjugates and methods IMMUNOME, INC. (US) 2025-04-22 US disclosed
US-12274754-B2 Immunoconjugates and methods IMMUNOME, INC. (US) 2025-04-15 US disclosed
US-12268750-B2 Immunoconjugates and methods IMMUNOME, INC. (US) 2025-04-08 US disclosed
US-20240424124-A1 IMMUNOCONJUGATES AND METHODS ZENO MANAGEMENT, INC. 2024-12-26 US disclosed
US-20240424121-A1 IMMUNOCONJUGATES AND METHODS ZENO MANAGEMENT, INC. 2024-12-26 US disclosed
US-20240424123-A1 IMMUNOCONJUGATES AND METHODS ZENO MANAGEMENT, INC. 2024-12-26 US disclosed
US-6436365-B2 ADMINISTRATION VIA CATHETER OF RADIOACTIVE METAL COMPLEX TO SITE OF LEGION; TREATMENT OF ATHERSCLEROSIS; REDUCES UNDESIRED RADIOACTIVE EXPOSURE OF HEALTHY TISSUE SCHERING AKTIENGESELLSCHAFT (DE) 2002-08-20 US disclosed
US-20020004031-A1 PROCESS FOR THERAPEUTIC TREATMENT OF PROLIFERATIVE DISEASES SCHERING AKTIENGESELLSCHAFT (DE) 2002-01-10 US disclosed
EP-1011737-A2 METHOD FOR TREATING PROLIFERATIVE DISEASES BY THERAPY SCHERING AKTIENGESELLSCHAFT (DE) 2000-06-28 EP disclosed
CN-1254295-A Surface-coated spring, method for the production thereof and use thereof for preventing restenosis SCHERING AG (DE) 2000-05-24 CN disclosed
EP-0979108-A2 STENTS WITH A RADIOACTIVE SURFACE COATING, PROCESSES FOR PRODUCING THE SAME AND THEIR USE FOR RESTENOSIS PREVENTION SCHERING AKTIENGESELLSCHAFT (DE) 2000-02-16 EP disclosed
WO-1999013920-A2 METHOD FOR TREATING PROLIFERATIVE DISEASES BY THERAPY SCHERING AKTIENGESELLSCHAFT (DE) 1999-03-25 WO disclosed
WO-1998048851-A2 STENTS WITH A RADIOACTIVE SURFACE COATING SCHERING AKTIENGESELLSCHAFT (DE) 1998-11-05 WO disclosed
US-4732970-A Antitumor amino acid and peptide derivatives of 1,4-bis(aminoalkyl and hydroxy-aminoalkyl)amino)-5,8-dihydroxyanthraquinones AMERICAN CYANAMID COMPANY (US) 1988-03-22 US disclosed
EP-0197478-A1 Diphosphonic-acid derivatives, process for preparing them and medicines containing these compounds Roche Diagnostics GmbH (DE) 1986-10-15 EP disclosed
US-4388233-A PROTEOLYTIC ENZYMES, FLUORIMETRIC ANALYSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1983-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280121-B2 Immunoconjugates and methods CD4, L1CAM, PDCD1LG2 ALDH1A1 120/4885TPSAB1 1906/4885TPSD1 1911/4885
US-12545716-B2 Immunoconjugates and methods FCGR3B, FCGR2A, LY6K ALDH1A1 1189/4885TPSAB1 1556/4885TPSD1 2404/4885
US-20240424121-A1 IMMUNOCONJUGATES AND METHODS CD4, L1CAM, PDCD1LG2 ALDH1A1 120/4885TPSAB1 1906/4885TPSD1 1911/4885
US-20020004031-A1 PROCESS FOR THERAPEUTIC TREATMENT OF PROLIFERATIVE DISEASES MKI67, FGF2, FGFR1 ALDH1A1 1488/4885TPSAB1 627/4885TPSD1 2344/4885
US-12503489-B2 Method for producing antibody-drug conjugate UGT1A9, ALB, MRPL21 ALDH1A1 257/4885TPSAB1 1890/4885TPSD1 4713/4885
US-12268750-B2 Immunoconjugates and methods CD4, L1CAM, PDCD1LG2 ALDH1A1 120/4885TPSAB1 1906/4885TPSD1 1911/4885
US-12274754-B2 Immunoconjugates and methods CD4, L1CAM, PDCD1LG2 ALDH1A1 120/4885TPSAB1 1906/4885TPSD1 1911/4885
US-20240424124-A1 IMMUNOCONJUGATES AND METHODS CD4, L1CAM, PDCD1LG2 ALDH1A1 120/4885TPSAB1 1906/4885TPSD1 1911/4885
US-20240424123-A1 IMMUNOCONJUGATES AND METHODS CD4, L1CAM, PDCD1LG2 ALDH1A1 120/4885TPSAB1 1906/4885TPSD1 1911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.