Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 7/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25007851 | 0.98 | CES2 (0.40) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL21025679 | 0.95 | MEN1 (0.38) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL19645215 | 0.94 | ALDH1A1 (0.38) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL18799385 | 0.87 | MEN1 (0.38) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL21015909 | 0.84 | HSP90AA1 (0.46) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL21015821 | 0.84 | CES2 (0.42) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL23770099 | 0.82 | LMNA (0.41) | MEN1KMT2A | |
| SCHEMBL23482569 | 0.81 | MEN1 (0.42) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL23015887 | 0.79 | FAAH (0.39) | MEN1MAPTKMT2AATML3MBTL1 | |
| SCHEMBL25983526 | 0.79 | ALDH1A1 (0.44) | MEN1MAPTKMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828378-B2 | Kinase inhibitors and methods of use | INTELLIKINE LLC (US) | 2017-11-28 | — | — | US | disclosed |