Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729414 | 0.98 | RAPGEF4 (0.44) | RAPGEF4NOTUMPGK1PGK2TAS2R14 | |
| SCHEMBL26745203 | 0.98 | RAPGEF4 (0.40) | RAPGEF4NOTUMPGK1PGK2TAS2R14 | |
| SCHEMBL25968108 | 0.96 | RAPGEF4 (0.43) | RAPGEF4NOTUMPGK1PGK2TAS2R14 | |
| SCHEMBL19668955 | 0.96 | RAPGEF4 (0.43) | RAPGEF4NOTUMPGK1PGK2TAS2R14 | |
| SCHEMBL25633935 | 0.87 | TAS2R14 (0.40) | RAPGEF4PGK1PGK2TAS2R14KIF11 | |
| SCHEMBL22105646 | 0.87 | TAS2R14 (0.40) | RAPGEF4PGK1PGK2TAS2R14KIF11 | |
| SCHEMBL41567 | 0.83 | CES2 (0.44) | RAPGEF4MAPTKIF11CES2XPO1 | |
| SCHEMBL30509222 | 0.81 | CES2 (0.39) | RAPGEF4MAPTKIF11CES2XPO1 | |
| SCHEMBL29557826 | 0.81 | RAPGEF4 (0.46) | RAPGEF4PGK1PGK2MAPTCES2 | |
| SCHEMBL27959140 | 0.81 | RAPGEF4 (0.46) | RAPGEF4PGK1PGK2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828259-B2 | Excage: synthesis of viologen-like pyridinium-based cages for the selective capture of polycyclic aromatic hydrocarbons | NORTHWESTERN UNIVERSITY (US) | 2017-11-28 | — | — | US | disclosed |