SCHEMBL25633935

SCHEMBL25633935

Cc1cc(C)cc([B-](c2ccccc2)(c2cc(C)cc(C(F)(F)F)c2)c2cc(C)cc(C(F)(F)F)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 1/20 0.40
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KIF11 P52732 1/20 0.38
FLT1 P17948 1/20 0.34
FLT4 P35916 1/20 0.34
KDR P35968 1/20 0.34
RAPGEF4 Q8WZA2 2/20 0.34
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
TACR1 P25103 5/20 0.33
LMNA P02545 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPK1 P28482 1/20 0.32
KRAS P01116 1/20 0.32
SOS1 Q07889 1/20 0.32
METAP2 P50579 1/20 0.32
P2RX1 P51575 1/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22105646 0.97 TAS2R14 (0.40) TAS2R14TSHRALDH1A1KIF11FLT1
SCHEMBL26745203 0.89 RAPGEF4 (0.40) TAS2R14TSHRKIF11RAPGEF4PGK1
SCHEMBL19668955 0.87 RAPGEF4 (0.43) TAS2R14RAPGEF4PGK1PGK2P2RX1
SCHEMBL25968108 0.87 RAPGEF4 (0.43) TAS2R14RAPGEF4PGK1PGK2P2RX1
SCHEMBL19645280 0.87 RAPGEF4 (0.41) TAS2R14KIF11RAPGEF4PGK1PGK2
SCHEMBL21729414 0.85 RAPGEF4 (0.44) TAS2R14KIF11RAPGEF4PGK1PGK2
SCHEMBL15065839 0.85 ALDH1A1 (0.48) TSHRALDH1A1KIF11TACR1METAP2
SCHEMBL5909720 0.85 ALDH1A1 (0.48) TSHRALDH1A1KIF11TACR1METAP2
SCHEMBL5909751 0.83 ACHE (0.41) TSHRALDH1A1TACR1LMNAMETAP2
Toluene SCHEMBL6538388 0.82 TSHR (0.41) TAS2R14TSHRALDH1A1KIF11RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208200-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING PRINTING PLATE FUJIFILM CORPORATION (JP) 2024-06-27 US disclosed
US-20230384671-A1 LAMINATE OF NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
US-20230150254-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-05-18 US disclosed