SCHEMBL19645907

SCHEMBL19645907

Cc1ccc(N(C)c2ccc(CCc3ccc4c(c3)c3cc(C)ccc3n4C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HRH1 P35367 2/20 0.39
HTR6 P50406 2/20 0.39
ADRA2A P08913 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR7 P34969 1/20 0.39
ADRA1A P35348 1/20 0.39
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
PLA2G4A P47712 2/20 0.38
ALOX15 P16050 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 1/20 0.35
NR1I2 O75469 1/20 0.35
AHR P35869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22083899 0.81 DHFR (0.43) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL21030547 0.80 KDM4E (0.46) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL2604392 0.75 MAPT (0.50) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL14465390 0.75 GPR3 (0.50) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL793546 0.74 BCHE (0.56) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL25620763 0.73 KDM4E (0.53) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL24797174 0.72 MAPT (0.41) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL13569441 0.71 CYP2C19 (0.55) ALDH1A1TDP1LMNA
SCHEMBL12083709 0.70 KDM4E (0.56) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL19645931 0.70 KDM4E (0.40) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9831042-B2 Organic dyes comprising a hydrazone moiety and their use in dye-sensitized solar cells BASF SE (DE) 2017-11-28 US disclosed