SCHEMBL2604392

SCHEMBL2604392

CCc1ccc2c(c1)c1cc(C)ccc1n2C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
KDM4E B2RXH2 4/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 1/20 0.50
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
GAA P10253 1/20 0.43
PGR P06401 2/20 0.43
RORA P35398 2/20 0.43
RORC P51449 2/20 0.43
RORB Q92753 2/20 0.43
NR1I2 O75469 1/20 0.41
AHR P35869 1/20 0.41
HTT P42858 2/20 0.41
APAF1 O14727 1/20 0.41
PKM P14618 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604386 0.90 ALDH1A1 (0.58) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL793546 0.84 BCHE (0.56) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL13067443 0.84 ALDH1A1 (0.54) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL25620763 0.84 KDM4E (0.53) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL14984333 0.83 ALDH1A1 (0.51) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL2604391 0.81 GPR3 (0.59) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL10067484 0.81 MAPT (0.40) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL21030547 0.81 KDM4E (0.46) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL6940359 0.80 BCHE (0.53) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL23988585 0.80 GPR3 (0.52) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10276803-B2 Organic light-emitting device, and light-emitting material and compound used therefor KYULUX, INC. (JP) 2019-04-30 US disclosed
US-20170256720-A1 ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR KYULUX, INC. (JP) 2017-09-07 US disclosed
EP-2714659-B1 COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS AMERICAN DYE SOURCE INC (CA) 2017-07-05 EP disclosed
US-9123858-B2 Method for manufacturing photoelectric conversion device and a solid-state imaging device having a photoelectric conversion device formed in accordance with the method FUJIFILM CORPORATION (JP) 2015-09-01 US disclosed
US-9123858-B2 Method for manufacturing photoelectric conversion device and a solid-state imaging device having a photoelectric conversion device formed in accordance with the method FUJIFILM CORPORATION (JP) 2015-09-01 US disclosed
US-8994132-B2 Photoelectric conversion element, solid-sate imaging element, imaging apparatus, and method for manufacturing photoelectric conversion element FUJIFILM CORPORATION (JP) 2015-03-31 US disclosed
US-8994132-B2 Photoelectric conversion element, solid-sate imaging element, imaging apparatus, and method for manufacturing photoelectric conversion element FUJIFILM CORPORATION (JP) 2015-03-31 US disclosed
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-8847208-B2 Photoelectric conversion device and imaging device having decreased dark current FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20120313142-A1 IMAGING DEVICE, METHOD FOR FABRICATING IMAGING DEVICE, AND IMAGING APPARATUS FUJIFILM CORPORATION (JP) 2012-12-13 US disclosed
US-20120313142-A1 IMAGING DEVICE, METHOD FOR FABRICATING IMAGING DEVICE, AND IMAGING APPARATUS FUJIFILM CORPORATION (JP) 2012-12-13 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120074513-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-SATE IMAGING ELEMENT, IMAGING APPARATUS, AND METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-20120074513-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-SATE IMAGING ELEMENT, IMAGING APPARATUS, AND METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10276803-B2 Organic light-emitting device, and light-emitting material and compound used therefor CRY1, WEE1, OR51E2 MAPT 2112/4885KDM4E 3233/4885ALDH1A1 80/4885
US-20170256720-A1 ORGANIC LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING MATERIAL AND COMPOUND USED THEREFOR CRY1, WEE1, OR51E2 MAPT 2112/4885KDM4E 3233/4885ALDH1A1 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.