Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23582823 | 0.82 | LPL (0.33) | CA1CA2CA9LPLLIPG | |
| SCHEMBL13983399 | 0.81 | LPL (0.32) | LPLLIPG | |
| SCHEMBL29573177 | 0.81 | LIPE (0.40) | SNCACA1CA2CA9ALDH1A1 | |
| SCHEMBL16706961 | 0.81 | ERN1 (0.38) | CA1CA2CA9UCHL1ALDH1A1 | |
| SCHEMBL24266097 | 0.81 | LIPE (0.40) | SNCACA1CA2CA9ALDH1A1 | |
| SCHEMBL1135193 | 0.79 | ALDH1A1 (0.50) | SNCACA1CA2CA9UCHL1 | |
| SCHEMBL19777737 | 0.78 | DGAT1 (0.36) | SNCA | |
| SCHEMBL13127061 | 0.74 | ACACB (0.39) | LPLLIPGALDH1A1 | |
| SCHEMBL1135188 | 0.74 | ERN1 (0.40) | CA1CA2CA9LPLLIPG | |
| SCHEMBL1498828 | 0.74 | MAOB (0.35) | SNCACA1CA2CA9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164331-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2017-11-29 | — | — | EP | disclosed |