Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101726 | 0.84 | CTSV (0.39) | MAPTCYP2C19BCHECTSVCTSL | |
| SCHEMBL19292430 | 0.83 | CTSV (0.38) | MAPTCYP2C19BCHECTSVCTSL | |
| SCHEMBL19962794 | 0.83 | BCHE (0.38) | MAPTCYP2C19BCHECTSVCTSL | |
| SCHEMBL19644574 | 0.83 | CTSL (0.36) | MAPTCYP2C19BCHECTSVCTSL | |
| SCHEMBL12310817 | 0.70 | CTSV (0.39) | MAPTCYP2C19CTSVCTSLCTSB | |
| SCHEMBL19997427 | 0.70 | BCHE (0.41) | CYP2C19BCHEIDO1ALDH1A1 | |
| SCHEMBL19088039 | 0.69 | CTSV (0.40) | MAPTCYP2C19BCHECTSVCTSL | |
| SCHEMBL24158036 | 0.68 | BCHE (0.44) | CYP2C19BCHECTSVCTSLCTSB | |
| SCHEMBL3300637 | 0.67 | LMNA (0.41) | BCHECTSVCTSLCTSBCTSS | |
| SCHEMBL24168933 | 0.67 | LMNA (0.41) | BCHECTSVCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709613-B1 | METHODS FOR TREATING HCV | GILEAD PHARMASSET LLC (US) | 2017-11-29 | — | — | EP | disclosed |