SCHEMBL19658243

SCHEMBL19658243

N#Cc1ccc(N(c2ccc(C#N)cc2)c2ccc(C=C3C(=O)c4ccccc4C3=O)o2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.48
POLB P06746 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
PKM P14618 3/20 0.48
CTDSP1 Q9GZU7 2/20 0.48
HPGD P15428 2/20 0.48
RECQL P46063 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPK1 P28482 1/20 0.48
MCL1 Q07820 1/20 0.48
ALDH1A1 P00352 4/20 0.40
HTT P42858 2/20 0.40
KMT2A Q03164 7/20 0.40
MEN1 O00255 6/20 0.40
BRAF P15056 1/20 0.37
KDM4E B2RXH2 2/20 0.37
AKT1 P31749 1/20 0.37
PPM1G O15355 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPN7 P35236 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19652011 0.85 MAPT (0.56) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652012 0.83 MAPT (0.51) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652016 0.83 MAPT (0.51) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652022 0.81 MAPT (0.49) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL22108589 0.79 MAPT (0.41) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL22108583 0.78 BRAF (0.51) MAPTPOLBL3MBTL1TDP1MAPK1
SCHEMBL19652010 0.78 MAPT (0.46) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652018 0.75 MAPT (0.44) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL22108465 0.75 MAPT (0.54) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL22108586 0.74 MAOA (0.44) MAPTPOLBL3MBTL1PKMCTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 MAPT 2370/4885POLB 1592/4885L3MBTL1 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.