SCHEMBL196532

SCHEMBL196532

O=C1N=NC=C1Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CALM1 P0DP23 1/20 0.42
PTPN1 P18031 1/20 0.42
SORT1 Q99523 1/20 0.41
MEN1 O00255 1/20 0.39
ELANE P08246 1/20 0.39
KMT2A Q03164 1/20 0.39
TEK Q02763 1/20 0.38
CTRC Q99895 3/20 0.37
DAO P14920 1/20 0.37
PARP1 P09874 1/20 0.36
AR P10275 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11030905 0.81 DAO (0.38) MAOBDAO
SCHEMBL8955069 0.79 DAO (0.44) MEN1KMT2ADAO
SCHEMBL4414748 0.77 ALDH1A1 (0.44) MEN1KMT2A
SCHEMBL11785859 0.68 PNMT (0.43) MEN1KMT2A
SCHEMBL2515239 0.67 MAOA (0.69) MAOAMAOBCALM1PTPN1MEN1
SCHEMBL991827 0.65 MAOA (0.50) MAOAMAOBPTPN1
SCHEMBL8132266 0.64 CALM1 (0.55) MAOAMAOBCALM1SORT1MEN1
SCHEMBL94148 0.64 MAOA (0.48) MAOAMAOBCALM1PTPN1MEN1
SCHEMBL981530 0.64 MAOA (0.44) MAOAMAOBCALM1PTPN1SORT1
SCHEMBL2339223 0.64 CALM1 (0.42) MAOAMAOBCALM1PTPN1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115919663-A Hair dyeing essential oil and preparation method thereof 广州市芊彩化妆品有限公司 2023-04-07 CN claimed
CN-115350112-A Hair dyeing composition, preparation method and application thereof, and hair dyeing mousse 广州艾柔生物科技有限公司 2022-11-18 CN claimed
CN-113143801-B Antioxidant scalp isolation muscle base solution and hair dye and preparation method thereof 泉后(广州)生物科技研究院有限公司 2022-10-04 CN claimed
US-20220242827-A1 PHENYLMETHYLPYRAZOLONE COMPOUND HAVING A NOVEL CRYSTAL FORM, AND METHOD FOR PRODUCING SAME SIA EMTEKO HOLDING (LV) 2022-08-04 US claimed
CN-114732746-A Low-irritation hair dyeing cream and preparation method thereof 广东歌秀科技有限公司 2022-07-12 CN claimed
CN-114585417-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-06-03 CN claimed
CN-114425027-A Hair dye and preparation method thereof 广州市芊彩化妆品有限公司 2022-05-03 CN claimed
CN-114423500-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-29 CN claimed
CN-114364361-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-15 CN claimed
CN-114364367-A Composition for dyeing keratin fibers and use thereof 莱雅公司 2022-04-15 CN claimed
EP-1670423-A1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2006-06-21 EP claimed
EP-1671619-A1 Hair colouring compositions The Procter and Gamble Company (US) 2006-06-21 EP claimed
WO-2006060570-A2 HAIR COLOURING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2006-06-08 WO claimed
US-20060117494-A1 Hair colouring compositions THE PROCTER & GAMBLE COMPANY 2006-06-08 US claimed
EP-1660022-A2 AGENT FOR COLOURING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2006-05-31 EP claimed
WO-2005044208-A1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2005-05-19 WO claimed
WO-2005032502-A2 AGENT FOR COLOURING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2005-04-14 WO claimed
US-20030097720-A1 Hairdye composition including 1-phenyl-3-methyl-5-pyrazolone and method for obtaining the same DONG SUNG PHARMACEUTICALS CO., LTD. (KR) 2003-05-29 US claimed
EP-1314418-A1 Hairdye composition including 1-phenyl-3-methyl-5-pyrazolone and method for obtaining the same Dong Sung pharmaceuticals Co., Ltd. (KR) 2003-05-28 EP claimed
US-3939140-A Process for the preparation of a dyestuff consisting substantially of only unsymmetrical 1:2-chromium complex azo dyestuffs HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242827-A1 PHENYLMETHYLPYRAZOLONE COMPOUND HAVING A NOVEL CRYSTAL FORM, AND METHOD FOR PRODUCING SAME AGPS, AAK1, CYP4B1 MAOA 371/4885MAOB 1497/4885CALM1 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.