Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19655001 | 0.84 | MAPT (0.35) | ABCB1ACHEMAPTALDH1A1 | |
| SCHEMBL19495005 | 0.82 | KDM4E (0.43) | ABCB1TGM2MAPTALDH1A1MEN1 | |
| SCHEMBL19655019 | 0.80 | USP2 (0.43) | GPR35ABCB1TGM2MAPTMEN1 | |
| SCHEMBL19494844 | 0.79 | AR (0.46) | ABCB1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19494880 | 0.79 | ABCB1 (0.45) | ABCB1TGM2MAPTALDH1A1MEN1 | |
| SCHEMBL19494832 | 0.79 | SOS1 (0.43) | CYP1A1TGM2MAPTALDH1A1MEN1 | |
| SCHEMBL12763951 | 0.76 | POLB (0.50) | ABCB1TGM2MAPTMEN1KMT2A | |
| SCHEMBL19494774 | 0.76 | USP2 (0.53) | ABCB1TGM2MAPTALDH1A1MEN1 | |
| SCHEMBL17109310 | 0.75 | ABCB1 (0.44) | ABCB1TGM2MAPTMEN1KMT2A | |
| SCHEMBL18854256 | 0.75 | FTO (0.51) | ABCB1TGM2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342031-A1 | QUENCHER | AHR, GFER, AKR1A1 | GPR35 1095/4885CYP1A1 10/4885CYP1B1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.