Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763951 | 0.86 | POLB (0.50) | KDM4EPOLBMYCFTOFPR2 | |
| SCHEMBL19494832 | 0.83 | SOS1 (0.43) | KDM4EPOLBFTOFPR2KMT2A | |
| SCHEMBL19495004 | 0.82 | L3MBTL1 (0.34) | POLBFPR2KMT2AMEN1ATM | |
| SCHEMBL19655000 | 0.82 | GPR35 (0.38) | KMT2AMEN1TGM2ALDH1A1MAPT | |
| SCHEMBL19494774 | 0.80 | USP2 (0.53) | KDM4EPOLBFTOFPR2KMT2A | |
| SCHEMBL18854256 | 0.79 | FTO (0.51) | KDM4EPOLBMYCFTOFPR2 | |
| SCHEMBL19655002 | 0.79 | FTO (0.46) | KDM4EPOLBFTOFPR2KMT2A | |
| SCHEMBL17109310 | 0.79 | ABCB1 (0.44) | KDM4EPOLBFTOFPR2KMT2A | |
| SCHEMBL26472325 | 0.78 | FTO (0.42) | KDM4EPOLBMYCFTOFPR2 | |
| SCHEMBL19494844 | 0.77 | AR (0.46) | KDM4EPOLBFTOFPR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
| EP-3235876-A1 | QUENCHER | Wako Pure Chemical Industries, Ltd. (JP) | 2017-10-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342031-A1 | QUENCHER | AHR, GFER, AKR1A1 | KDM4E 3254/4885POLB 1849/4885MYC 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.