Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26472325 | 0.92 | FTO (0.42) | FPR2FTOTLR7USP2KDM4E | |
| SCHEMBL19655014 | 0.87 | FTO (0.40) | FPR2FTOTLR7USP2KDM4E | |
| SCHEMBL29822272 | 0.87 | FTO (0.40) | FPR2FTOTLR7USP2KDM4E | |
| SCHEMBL19655016 | 0.87 | FPR2 (0.34) | FPR2TLR7USP2TGM2ABCB1 | |
| SCHEMBL19655017 | 0.83 | FTO (0.39) | FPR2FTOTLR7USP2KDM4E | |
| SCHEMBL19494852 | 0.80 | KDM4E (0.41) | FTOUSP2KDM4EMEN1BLM | |
| SCHEMBL19085489 | 0.76 | FPR2 (0.45) | FPR2FTOTLR7USP2KDM4E | |
| SCHEMBL12763951 | 0.75 | POLB (0.50) | FPR2FTOTLR7USP2KDM4E | |
| SCHEMBL19655013 | 0.75 | ABCB1 (0.36) | FPR2TLR7USP2TGM2ABCB1 | |
| SCHEMBL19495010 | 0.74 | KDM4E (0.41) | FTOUSP2KDM4EMEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342031-A1 | QUENCHER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342031-A1 | QUENCHER | AHR, GFER, AKR1A1 | FPR2 83/4885FTO 330/4885TLR7 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.