SCHEMBL19655201

SCHEMBL19655201

c1ccc(-c2cc(-c3ccccc3)cc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc(-c7nc8ccccc8nc7-c7ccccc7)c6)c5c43)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
GAA P10253 4/20 0.40
MEN1 O00255 3/20 0.40
HSD17B10 Q99714 2/20 0.38
POLB P06746 1/20 0.38
KDM4E B2RXH2 5/20 0.37
L3MBTL1 Q9Y468 4/20 0.37
ATM Q13315 2/20 0.37
ALDH1A1 P00352 5/20 0.36
LMNA P02545 3/20 0.36
THRB P10828 1/20 0.36
PDE10A Q9Y233 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 1/20 0.35
DHODH Q02127 1/20 0.35
TLR9 Q9NR96 1/20 0.35
HPGD P15428 1/20 0.35
CFTR P13569 2/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655194 0.95 KMT2A (0.41) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655191 0.94 L3MBTL1 (0.41) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655218 0.94 L3MBTL1 (0.41) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655196 0.94 L3MBTL1 (0.44) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655195 0.93 L3MBTL1 (0.41) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655399 0.90 MEN1 (0.40) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655206 0.89 L3MBTL1 (0.43) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655310 0.89 L3MBTL1 (0.41) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655211 0.88 GSR (0.40) KMT2AGAAMEN1HSD17B10POLB
SCHEMBL19655210 0.88 MEN1 (0.39) KMT2AGAAMEN1HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO KMT2A 3170/4885GAA 2621/4885MEN1 2827/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO KMT2A 3170/4885GAA 2621/4885MEN1 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.