SCHEMBL19655203

SCHEMBL19655203

c1ccc(-c2nc3ccccc3nc2-c2cccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc7c6sc6c(-c8ccccc8)cccc67)c5c43)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PDE10A Q9Y233 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
LIMK1 P53667 1/20 0.33
HSD17B10 Q99714 2/20 0.32
POLB P06746 1/20 0.32
ALDH1A1 P00352 4/20 0.31
LMNA P02545 3/20 0.31
KDM4E B2RXH2 2/20 0.31
THRB P10828 1/20 0.31
MAPT P10636 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655250 0.91 LIMK1 (0.34) LIMK1
SCHEMBL19655419 0.91 PDE10A (0.34) GAAMEN1KMT2APDE10AL3MBTL1
SCHEMBL19655192 0.89 MEN1 (0.34) GAAMEN1KMT2APDE10AL3MBTL1
SCHEMBL19653921 0.88 PDE10A (0.33) GAAMEN1KMT2APDE10AL3MBTL1
SCHEMBL19655183 0.87 LIMK1 (0.34) GAAMEN1KMT2APDE10AL3MBTL1
SCHEMBL19655196 0.84 L3MBTL1 (0.44) GAAMEN1KMT2AL3MBTL1HSD17B10
SCHEMBL19655211 0.83 GSR (0.40) GAAMEN1KMT2APDE10AL3MBTL1
SCHEMBL19655200 0.83 MEN1 (0.34) GAAMEN1KMT2APDE10AL3MBTL1
SCHEMBL19655201 0.83 KMT2A (0.40) GAAMEN1KMT2APDE10AL3MBTL1
SCHEMBL19655194 0.83 KMT2A (0.41) GAAMEN1KMT2APDE10AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO GAA 2621/4885MEN1 2827/4885KMT2A 3170/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO GAA 2621/4885MEN1 2827/4885KMT2A 3170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.