Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022074 | 1.00 | KDM1A (0.56) | KDM1AMAOAMAOBLMNAKMT2A | |
| SCHEMBL19953764 | 0.92 | KDM1A (0.60) | KDM1AMAOAMAOBLMNAKMT2A | |
| SCHEMBL13448854 | 0.86 | KDM1A (0.65) | KDM1AMAOAMAOBKMT2ACYP1A2 | |
| SCHEMBL31428579 | 0.85 | KDM1A (0.53) | KDM1AMAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL2092750 | 0.81 | KDM1A (0.52) | KDM1AMAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL31238944 | 0.80 | CXCR4 (0.69) | LMNAKMT2ACXCR4HRH3USP2 | |
| SCHEMBL24503809 | 0.76 | KDM1A (0.48) | KDM1AMAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL3097499 | 0.76 | FAAH (0.54) | KDM1AMAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL24943587 | 0.74 | HDAC1 (0.55) | KDM1AMAOAMAOBCYP1A2NPC1 | |
| SCHEMBL9128660 | 0.74 | PABPC1 (0.53) | LMNAKMT2ACYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307820-B | Quinoline ring-substituted aminophenoxy zinc complex and preparation method and application thereof | 华东理工大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-113307820-A | Quinoline ring-substituted aminophenoxy zinc complex and preparation method and application thereof | 华东理工大学 | 2021-08-27 | — | — | CN | disclosed |
| EP-3464418-B1 | POLYMERS, PROCESSES, COMPOSITIONS & USES | DSM IP ASSETS BV (NL) | 2020-11-18 | — | — | EP | disclosed |
| WO-2017203044-A2 | POLYMERS, PROCESSES, COMPOSITIONS & USES | DSM IP ASSETS B.V. (NL) | 2017-11-30 | — | — | WO | disclosed |