Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654345 | 0.98 | FAAH (0.56) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7504454 | 0.83 | FAAH (0.52) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31019207 | 0.83 | FAAH (0.52) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL16825153 | 0.82 | FAAH (0.51) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20515340 | 0.78 | FAAH (0.47) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8965425 | 0.77 | CYSLTR1 (0.64) | CYSLTR2CYSLTR1ALOX5HDAC6 | |
| SCHEMBL1256827 | 0.76 | CYP1A2 (0.75) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16654084 | 0.76 | PDE10A (0.56) | CYP1A2CYP2C9ALDH1A1KDM4ERAB9A | |
| SCHEMBL30022074 | 0.76 | KDM1A (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19656391 | 0.76 | KDM1A (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399673-B2 | Substituted 2-mercaptoquinoline-3-carboxamides as KCNQ2/3 modulators | GRUENENTHAL GMBH (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20120252841-A1 | Substituted 2-mercaptoquinoline-3-carboxamides as KCNQ2/3 modulators | DRUNENTHAL GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20100234372-A1 | SUBSTITUTED 2-MERCAPTOQUINOLINE-3-CARBOXAMIDES AS KCNQ2/3 MODULATORS | GRUNENTHAL GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234372-A1 | SUBSTITUTED 2-MERCAPTOQUINOLINE-3-CARBOXAMIDES AS KCNQ2/3 MODULATORS | KCNQ1, KCNQ2, KCNJ2 | FAAH 1779/4885CYP1A2 1298/4885CYP3A4 857/4885 |
| US-20120252841-A1 | Substituted 2-mercaptoquinoline-3-carboxamides as KCNQ2/3 modulators | KCNQ1, KCNQ2, KCNJ2 | FAAH 1779/4885CYP1A2 1298/4885CYP3A4 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.