SCHEMBL19652018

SCHEMBL19652018

O=C1C(=Cc2ccc(N(c3ccccc3)c3ccccc3)o2)C(=O)c2cc3ccccc3cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.44
L3MBTL1 Q9Y468 10/20 0.44
POLB P06746 8/20 0.44
PKM P14618 5/20 0.44
TDP1 Q9NUW8 4/20 0.44
HPGD P15428 4/20 0.44
RECQL P46063 3/20 0.44
CTDSP1 Q9GZU7 3/20 0.44
MAPK1 P28482 3/20 0.44
MCL1 Q07820 1/20 0.44
KMT2A Q03164 10/20 0.40
MEN1 O00255 9/20 0.40
ALDH1A1 P00352 7/20 0.40
GAA P10253 2/20 0.40
HSP90AA1 P07900 1/20 0.40
APEX1 P27695 1/20 0.40
AKT1 P31749 1/20 0.39
PPM1G O15355 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPN7 P35236 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22108611 0.97 MAPT (0.43) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL19652015 0.90 MAPT (0.41) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL19652010 0.89 MAPT (0.46) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL19652011 0.89 MAPT (0.56) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL19652026 0.83 DNMT1 (0.40) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL19652022 0.82 MAPT (0.49) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL19652008 0.80 MAPT (0.45) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL22108586 0.80 MAOA (0.44) MAPTL3MBTL1POLBPKMTDP1
SCHEMBL22238830 0.79 ADORA3 (0.31) ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1
SCHEMBL22108612 0.79 POLB (0.43) MAPTL3MBTL1POLBPKMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201294-B2 Photoelectric conversion element, optical sensor, imaging element, and compound FUJIFILM CORPORATION (JP) 2021-12-14 US disclosed
US-20200194679-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, IMAGING ELEMENT, AND COMPOUND FUJIFILM CORPORATION (JP) 2020-06-18 US disclosed
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200194679-A1 PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, IMAGING ELEMENT, AND COMPOUND PIN4, PIN1, CRY1 MAPT 774/4885L3MBTL1 4345/4885POLB 2865/4885
US-11201294-B2 Photoelectric conversion element, optical sensor, imaging element, and compound PIN4, PIN1, CRY1 MAPT 774/4885L3MBTL1 4345/4885POLB 2865/4885
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 MAPT 2370/4885L3MBTL1 3762/4885POLB 1592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.