Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233806 | 0.87 | RECQL (0.69) | RECQLSMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL1963543 | 0.84 | RECQL (0.63) | RECQLSMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL2145736 | 0.84 | RECQL (0.63) | RECQLSMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL2314609 | 0.81 | RECQL (0.59) | RECQLSMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL1965222 | 0.80 | PPARG (0.44) | SMN1; SMN2MAPTALDH1A1MAPK1MEN1 | |
| SCHEMBL2837952 | 0.80 | RECQL (0.57) | RECQLSMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL1962739 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTALDH1A1PLA2G1BPLA2G2A | |
| SCHEMBL3830729 | 0.78 | MEN1 (0.57) | SMN1; SMN2ALDH1A1PLA2G1BPLA2G2AADRA1D | |
| SCHEMBL825278 | 0.75 | SMN1; SMN2 (0.67) | RECQLSMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL17065552 | 0.75 | SMN1; SMN2 (0.67) | RECQLSMN1; SMN2NR5A2NR5A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052718-A9 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-06-16 | — | — | WO | disclosed |