Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.32 |
| ▸ | CHAT | P28329 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966094 | 1.00 | MTNR1A (0.34) | MTNR1AMTNR1BNPC1SMN1; SMN2KDM4E | |
| SCHEMBL3431702 | 1.00 | MTNR1A (0.34) | MTNR1AMTNR1BNPC1SMN1; SMN2KDM4E | |
| SCHEMBL1773239 | 0.84 | FAAH (0.41) | MTNR1AMTNR1BNPC1SMN1; SMN2KDM4E | |
| SCHEMBL1773241 | 0.84 | FAAH (0.41) | MTNR1AMTNR1BNPC1SMN1; SMN2KDM4E | |
| SCHEMBL1775045 | 0.84 | FAAH (0.41) | MTNR1AMTNR1BNPC1SMN1; SMN2KDM4E | |
| SCHEMBL3376520 | 0.83 | CHAT (0.34) | MTNR1AMTNR1BNPC1SMN1; SMN2KDM4E | |
| SCHEMBL1996942 | 0.83 | SMYD3 (0.31) | — | |
| SCHEMBL20718927 | 0.80 | SMYD3 (0.30) | — | |
| SCHEMBL18192786 | 0.80 | TDP1 (0.33) | — | |
| SCHEMBL1963637 | 0.79 | SLC6A3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334669-B1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | BAYER IP GMBH (DE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2334669-A1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | Bayer CropScience AG (DE) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010037479-A1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-04-08 | — | — | WO | disclosed |